So you're getting around to building the buggergood stuff! As far as the dome is concerned, there are plently of high comp 18RG's out there running huge lift and long duration. Where are you getting the pistons from? When u get them made, if you give them a sample of the original pistons, they'll keep the new flycuts at the original depth, and design the dome accordingly. In all honesty, I don't think there is a significant difference between 10.5:1 pistons and 9.7:1 pistons, so if u can track down a set of early RG pistons, you'll be laughing.
Also, check out toysport's website. They are in america, but they sell 10.5:1 forged pistons for a very reasonable price.
Cam wise, as soon as you run higher compression, you need to run longer duration for lower dynamic compression. 272 degree cams should be about right, and the power will start to be useable around 3000rpm. You'd wanna run higher lift than stock too, and you should also consider getting the head ported. If u do get the head ported, it'll be put on a flow bench, and they'll be able to recommend a profile to suit the flow characteristics. So in a word... Don't worry about clearance issues with 10.5:1 pistons.
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