Assuming you're using the ZE pistons because of turbo application, you'll be able to run more boost safely. ZE pistons will lower CR and are stronger..
You've got to make sure the timing is set correctly before starting the car up otherwise your valves and pistons will kiss. Snapping a belt will also result in the piston meeting the valves. I honestly don't see a problem in this as long as you know for sure the timing is set correctly. Many motors are built as an interference motor from factory.
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