Yep, you certainly can.
I don't know all the little tricks, but most run a balance pipe a short distance after the collectors.
You can treat each bank of four like a seperate engine, but the 90deg crank of the V-8's has the extractor pipes in either the traditional 4-1 or if you go 4-2-1 then the end two ports have to join each other first, then those two secondaries into the final collector.
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